Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.G475G
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CYP2C9

NM_000771.4:p.G475G

Associated Papers

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc6.xlsx › Sheet1

Identification and in vitro functional assessment of 10 CYP2C9 variants found in Chinese Han subjects.

Zhang Q et al.

Frontiers in Endocrinology, 2023

Analytical validation of GenoPharm a clinical genotyping open array panel of 46 pharmacogenes inclusive of variants unique to people of African ancestry.

Kanji CR et al.

Plos One, 2023

Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation.

Muñiz P et al.

Frontiers in Immunology, 2022

36211438 (PubMed )
Supplement: Table_1.xlsx › Hoja1

PharmVar GeneFocus: CYP2C9.

Sangkuhl K et al.

Clinical Pharmacology and Therapeutics, 2021

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

Feasibility of Integrating Panel-Based Pharmacogenomics Testing for Chemotherapy and Supportive Care in Patients With Colorectal Cancer.

Kasi PM et al.

Technology in Cancer Research & Treatment, 2019

31533552 (PubMed )
Supplement: OneOme_sample_comprehensive_report.pdf

Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

Zhou SF et al.

Toxicology, 2010

A haplotype of CYP2C9 associated with warfarin sensitivity in mechanical heart valve replacement patients.

Lee SJ et al.

British Journal of Clinical Pharmacology, 2010

A warfarin-dosing model in Asians that uses single-nucleotide polymorphisms in vitamin K epoxide reductase complex and cytochrome P450 2C9.

Tham LS et al.

Clinical Pharmacology and Therapeutics, 2006

Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese.

Maekawa K et al.

Pharmacogenetics and Genomics, 2006

Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population.

Lee SC et al.

Clinical Pharmacology and Therapeutics, 2006

Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.

DeLozier TC et al.

The Journal of Pharmacology and Experimental Therapeutics, 2005

CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes.

Veenstra DL et al.

Clinical Pharmacology and Therapeutics, 2005

Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.

Zhao F et al.

Clinical Pharmacology and Therapeutics, 2004

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily.

Goldstein JA

British Journal of Clinical Pharmacology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."