Associated Papers
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
The impacts of natural product miltirone and the CYP2D6 pharmacogenetic phenotype on fluoxetine metabolism.
Zhang X et al.
Frontiers in Pharmacology, 2024
The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.
Zhou Y et al.
The Pharmacogenomics Journal, 2022
Benchmarking analysis of deleterious SNP prediction tools on CYP2D6 enzyme.
Ferreira KCDV et al.
Chemical Biology & Drug Design, 2020
Added Value of Clinical Sequencing: WGS-Based Profiling of Pharmacogenes.
Caspar SM et al.
International Journal of Molecular Sciences, 2020
Effects of 24 CYP2D6 variants found in Chinese population on the metabolism of clonidine in vitro.
Li XY et al.
Chemico-biological Interactions, 2019
Effect of 22 CYP2D6 variants found in the Chinese population on tolterodine metabolism in vitro.
Wang H et al.
Chemico-biological Interactions, 2017
In vitro assessment of 24 CYP2D6 allelic isoforms on the metabolism of methadone.
Su Y et al.
Drug Testing and Analysis, 2017
Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro.
Fang P et al.
Drug Design, Development and Therapy, 2017
Effect of 22 Novel Cytochrome P450 2D6 (CYP2D6) Variants Found in the Chinese Population on Hemangeol Metabolism In Vitro.
Liang B et al.
European Journal of Drug Metabolism and Pharmacokinetics, 2016
Effect of 24 cytochrome P450 2D6 variants found in the Chinese population on the N-demethylation of amitriptyline in vitro.
Weng Q et al.
Pharmaceutical Biology, 2016
Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro.
Hu X et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2016
Assessment of 25 CYP2D6 alleles found in the Chinese population on propafenone metabolism in vitro.
Su Y et al.
Canadian Journal of Physiology and Pharmacology, 2016
Functional characterization of 22 novel CYP2D6 variants for the metabolism of Tamoxifen.
Hu XX et al.
The Journal of Pharmacy and Pharmacology, 2016
Effect of CYP2D6 genetic polymorphism on the metabolism of citalopram in vitro.
Hu XX et al.
Drug Metabolism and Pharmacokinetics, 2016
Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro.
Cai J et al.
Basic & Clinical Pharmacology & Toxicology, 2016
Effect of CYP2D6 variants on venlafaxine metabolism in vitro.
Zhan YY et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2016
Effect of 24 Cytochrome P450 2D6 Variants Found in the Chinese Population on Atomoxetine Metabolism in vitro.
Liang B et al.
Pharmacology, 2016
Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine.
Xu RA et al.
Drug Design, Development and Therapy, 2016
Effects of 22 CYP2D6 Genetic Variations Newly Identified in Chinese Population on Olanzapine Metabolism in vitro.
Zhou HY et al.
Pharmacology, 2016
Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro.
Wang Z et al.
Drug Design, Development and Therapy, 2016
In vitro functional assessment of 22 newly identified CYP2D6 allelic variants in the Chinese population.
Dai DP et al.
Basic & Clinical Pharmacology & Toxicology, 2015
Effects of 24 CYP2D6 Variants Found in the Chinese Population on the Metabolism of Risperidone.
Wang ZH et al.
Pharmacology, 2015