Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.F481V
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CYP2D6

NM_000106.6:p.F481V

Associated Papers

The variation landscape of CYP2D6 in a multi-ethnic Asian population.

Maulana Y et al.

Scientific Reports, 2024

Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations.

Twesigomwe D et al.

Clinical Pharmacology and Therapeutics, 2023

36111505 (PubMed )
Supplement: CPT-113-643-s001.pdf

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies' adaptive sampling.

Deserranno K et al.

Frontiers in Pharmacology, 2023

38026945 (PubMed )
Supplement: DataSheet1.ZIP › SupplementaryMaterials › SupplementaryMaterials_Tables_S4-S9.xlsx › HG00190_R10.4.1_AldyCalls

Characterization of Novel CYP2D6 Alleles across Sub-Saharan African Populations.

Wang WY et al.

Journal of Personalized Medicine, 2022

36294714 (PubMed )
Supplement: jpm-12-01575-s001.zip › Supplemental_Table_S4__Allele_Variant_List.xlsx › Table

Supervised Classification of CYP2D6 Genotype and Metabolizer Phenotype With Postmortem Tramadol-Exposed Finns.

Wendt FR et al.

The American Journal of Forensic Medicine and Pathology, 2019

Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.

He ZX et al.

Drug Metabolism Reviews, 2015

Advances in molecular modeling of human cytochrome P450 polymorphism.

Martiny VY et al.

Journal of Molecular Biology, 2013

Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines.

Scheer N et al.

Molecular Pharmacology, 2012

Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol, and dextromethorphan.

Uno Y et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2010

Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

Zhou SF

Clinical Pharmacokinetics, 2009

Catalytic roles of CYP2D6.10 and CYP2D6.36 enzymes in mexiletine metabolism: in vitro functional analysis of recombinant proteins expressed in Saccharomyces cerevisiae.

Hanioka N et al.

Biochemical Pharmacology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."