Associated Papers
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
Molecular Mechanisms Underlying Single Nucleotide Polymorphism-Induced Reactivity Decrease in CYP2D6.
Becker D et al.
Journal of Chemical Information and Modeling, 2024
The variation landscape of CYP2D6 in a multi-ethnic Asian population.
Maulana Y et al.
Scientific Reports, 2024
The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.
Zhou Y et al.
The Pharmacogenomics Journal, 2022
Characterization of Novel CYP2D6 Alleles across Sub-Saharan African Populations.
Wang WY et al.
Journal of Personalized Medicine, 2022
Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.
Pernaute-Lau L et al.
Antimicrobial Agents and Chemotherapy, 2021
Determination of novel CYP2D6 haplotype using the targeted sequencing followed by the long-read sequencing and the functional characterization in the Japanese population.
Fukunaga K et al.
Journal of Human Genetics, 2021
Benchmarking analysis of deleterious SNP prediction tools on CYP2D6 enzyme.
Ferreira KCDV et al.
Chemical Biology & Drug Design, 2020
Challenges to assess substrate-dependent allelic effects in CYP450 enzymes and the potential clinical implications.
Marcath LA et al.
The Pharmacogenomics Journal, 2019
Impact of CYP2D6 polymorphisms on endoxifen concentrations and breast cancer outcomes.
Hwang GS et al.
The Pharmacogenomics Journal, 2018
Risperidone-associated adverse drug reactions and CYP2D6 polymorphisms in a South African cohort.
Dodgen TM et al.
Applied & Translational Genomics, 2015
Functional influence of human CYP2D6 allelic variations: P34S, E418K, S486T, and R296C.
Kim J et al.
Archives of Pharmacal Research, 2013
Expression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line.
Lee HJ et al.
Toxicological Research, 2011
Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans.
Lee SJ et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2009