Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.P412P
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CYP2D6

NM_000106.6:p.P412P

Associated Papers

Influence of ABCB1 polymorphisms on aripiprazole and dehydroaripiprazole plasma concentrations.

Toja-Camba FJ et al.

Scientific Reports, 2025

Pharmacogenomics of Cancer Pain Treatment Outcomes in Asian Populations: A Review.

Satkunananthan SE et al.

Journal of Personalized Medicine, 2022

Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults.

Pronk AC et al.

Plos One, 2022

Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics.

Koller D et al.

Advances in Therapy, 2021

33278020 (PubMed )
Supplement: 12325_2020_1566_MOESM1_ESM.docx

Major CYP450 Polymorphism among Saudi Patients.

Almeman AA

Drug Metabolism Letters, 2021

Genetic Polymorphisms of Pesticide-Metabolizing Enzymes and Transporters in Agricultural Workers and Thyroid Hormone Levels.

Sirivarasai J et al.

Risk Management and Healthcare Policy, 2021

ABCB1 gene variants as risk factors and modulators of age of onset of demyelinating disease in Mexican patients.

Guerrero Camacho JL et al.

Neurologia, 2020

How Can Drug Metabolism and Transporter Genetics Inform Psychotropic Prescribing?

Carvalho Henriques B et al.

Frontiers in Genetics, 2020

Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers.

Belmonte C et al.

Basic & Clinical Pharmacology & Toxicology, 2018

Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.

Arrigoni E et al.

International Journal of Molecular Sciences, 2017

Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision Medicine.

Ahmed S et al.

Genomics, Proteomics & Bioinformatics, 2016

Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.

Rodieux F et al.

Journal of Clinical Pharmacology, 2016

Association between selected gene polymorphisms and statin metabolism, risk of ischemic stroke and cardiovascular disorders.

Kotlęga D et al.

Postepy Higieny I Medycyny Doswiadczalnej (online), 2016

Pharmacogenetics of Drug-Induced QT Interval Prolongation: An Update.

Niemeijer MN et al.

Drug Safety, 2015

Pharmacogenetic study on risperidone long-acting injection: influence of cytochrome P450 2D6 and pregnane X receptor on risperidone exposure and drug-induced side-effects.

Choong E et al.

Journal of Clinical Psychopharmacology, 2013

ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram.

Karlsson L et al.

International Journal of Legal Medicine, 2013

Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.

Lai Y et al.

Expert Opinion on Drug Metabolism & Toxicology, 2012

Genotypic screening of the main opiate-related polymorphisms in a cohort of 139 sickle cell disease patients.

Joly P et al.

American Journal of Hematology, 2012

Cardiovascular pharmacogenetics.

Myburgh R et al.

Pharmacology & Therapeutics, 2012

Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.

Sai K et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.

Yuferov V et al.

Annals of the New York Academy of Sciences, 2010

Effect of genetic factors on opioid action.

Kosarac B et al.

Current Opinion in Anaesthesiology, 2009

Associations between common variants in the MDR1 (ABCB1) gene and ulcerative colitis among North Indians.

Juyal G et al.

Pharmacogenetics and Genomics, 2009

Pharmacogenomics: a tool for improving cancer chemotherapy.

Monzó M et al.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008

Determination of ABCB1 polymorphisms and haplotypes frequencies in a French population.

Jeannesson E et al.

Fundamental & Clinical Pharmacology, 2007

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

Cascorbi I

Pharmacology & Therapeutics, 2006

Implications of genetic polymorphisms in drug transporters for pharmacotherapy.

Kerb R

Cancer Letters, 2006

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

The MDR1 (ABCB1) gene polymorphism and its clinical implications.

Ieiri I et al.

Clinical Pharmacokinetics, 2004

Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.

Lötsch J et al.

Clinical Pharmacokinetics, 2004

CYP2D6 isoenzyme and ABCB1 gene polymorphisms associated with postoperative nausea and vomiting in women undergoing laparoscopic cholecystectomy: a randomized trial.

Ribeiro AHS et al.

Brazilian Journal of Anesthesiology (elsevier), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."