Associated Papers
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
The variation landscape of CYP2D6 in a multi-ethnic Asian population.
Maulana Y et al.
Scientific Reports, 2024
The impacts of natural product miltirone and the CYP2D6 pharmacogenetic phenotype on fluoxetine metabolism.
Zhang X et al.
Frontiers in Pharmacology, 2024
Case Report: The effective treatment of patients in advanced no-small cell lung cancer patients with EGFR G719X/S768I/L861Q and acquired MET amplification: A case series and literature review.
Zhao Y et al.
Frontiers in Oncology, 2023
Effects of CYP2D6 Genetic Polymorphism and Drug Interaction on the Metabolism of Dacomitinib.
Han M et al.
Chemical Research in Toxicology, 2022
Benchmarking analysis of deleterious SNP prediction tools on CYP2D6 enzyme.
Ferreira KCDV et al.
Chemical Biology & Drug Design, 2020
Effect of 22 CYP2D6 variants found in the Chinese population on tolterodine metabolism in vitro.
Wang H et al.
Chemico-biological Interactions, 2017
Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro.
Fang P et al.
Drug Design, Development and Therapy, 2017
Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro.
Hu X et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2016
Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro.
Cai J et al.
Basic & Clinical Pharmacology & Toxicology, 2016
Effect of CYP2D6 variants on venlafaxine metabolism in vitro.
Zhan YY et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2016
Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine.
Xu RA et al.
Drug Design, Development and Therapy, 2016
Effects of 22 CYP2D6 Genetic Variations Newly Identified in Chinese Population on Olanzapine Metabolism in vitro.
Zhou HY et al.
Pharmacology, 2016
Developing and Evaluating the HRM Technique for Identifying Cytochrome P450 2D6 Polymorphisms.
Lu HC et al.
Journal of Clinical Laboratory Analysis, 2015
Direct assessment of cytochrome P450 2D6 genotypes by high-resolution melting analysis and DNA sequencing.
Chang YS et al.
Environmental Toxicology and Pharmacology, 2014