Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.E334K
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CYP2D6

NM_000106.6:p.E334K

Associated Papers

Catalogue of Somatic Mutations in Cancer Database and Structural Modeling Analysis of CYP2D6 Mutations in Human Cancers.

Kuchinski K et al.

The Journal of Pharmacology and Experimental Therapeutics, 2024

Discovery and Enzyme Kinetic Characterization of Novel CYP2D6 Variants.

Zhong YS et al.

Chemical Research in Toxicology, 2024

Resolving discordant CYP2D6 genotyping results in Thai subjects: platform limitations and novel haplotypes.

Hongkaew Y et al.

Pharmacogenomics, 2021

The relationship between the CYP2D6 polymorphisms and tamoxifen efficacy in adjuvant endocrine therapy of breast cancer patients in Chinese Han population.

Lan B et al.

International Journal of Cancer, 2018

Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing.

Buermans HP et al.

Human Mutation, 2017

28044414 (PubMed )
Supplement: HUMU-38-310-s004.xlsx › Sup_Table_3

CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.

Gaedigk A et al.

The Journal of Molecular Diagnostics : Jmd, 2015

Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.

He ZX et al.

Drug Metabolism Reviews, 2015

Polymorphisms and phenotypic analysis of cytochrome P450 2D6 in the Tibetan population.

Jin TB et al.

Gene, 2013

Systematic functional study of cytochrome P450 2D6 promoter polymorphisms in the Chinese Han population.

Gong X et al.

Plos One, 2013

Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population.

Wright GE et al.

Annals of Human Genetics, 2010

Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans.

Lee SJ et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2009

Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

Zhou SF

Clinical Pharmacokinetics, 2009

Systematic polymorphism analysis of the CYP2D6 gene in four different geographical Han populations in mainland China.

Qin S et al.

Genomics, 2008

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.

Raimundo S et al.

Clinical Pharmacology and Therapeutics, 2004

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

Løvlie R et al.

Pharmacogenetics, 2001

Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects.

Ho MT et al.

Annals of Hepatology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."