Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.D301G
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CYP2D6

NM_000106.6:p.D301G

Associated Papers

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.

Wang B et al.

Drug Metabolism Reviews, 2009

Topological role of cytochrome P450 2D6 active site residues.

van Waterschoot RA et al.

Archives of Biochemistry and Biophysics, 2006

Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.

Lewis DF

Archives of Biochemistry and Biophysics, 2003

Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6.

Ellis SW et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."