Associated Papers
Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
Oliveira DM et al.
Oncotarget, 2018
29844865 (PubMed )
Supplement: oncotarget-09-23960-s003.xlsx › Supplemental_Table_S2
Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing - a case report.
Valtcheva N et al.
Bmc Cancer, 2017
28103826 (PubMed )
Supplement: 12885_2017_3054_MOESM1_ESM.xlsx › OvCa_caseI_run2
New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.
Wang B et al.
Drug Metabolism Reviews, 2009
Residues glutamate 216 and aspartate 301 are key determinants of substrate specificity and product regioselectivity in cytochrome P450 2D6.
Paine MJ et al.
The Journal of Biological Chemistry, 2003
Impact of incorporating the 2C5 crystal structure into comparative models of cytochrome P450 2D6.
Kirton SB et al.
Proteins, 2002
Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism.
Lewis DF et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 1997
Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6.
Ellis SW et al.
The Journal of Biological Chemistry, 1995
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