Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.L231R
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CYP2D6

NM_000106.6:p.L231R

Associated Papers

Molecular dynamics of CYP2D6 polymorphisms in the absence and presence of a mechanism-based inactivator reveals changes in local flexibility and dominant substrate access channels.

de Waal PW et al.

Plos One, 2014

Crystal structure of human cytochrome P450 2D6 with prinomastat bound.

Wang A et al.

The Journal of Biological Chemistry, 2012

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.

Wang B et al.

Drug Metabolism Reviews, 2009

Crystal structure of human cytochrome P450 2D6.

Rowland P et al.

The Journal of Biological Chemistry, 2006

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