Associated Papers
Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6.
McCarty KD et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021
Crystal Structures of Drug-Metabolizing CYPs.
Estrada DF et al.
Methods in Molecular Biology (clifton, N.j.), 2021
Crystal structure of human cytochrome P450 2D6 with prinomastat bound.
Wang A et al.
The Journal of Biological Chemistry, 2012
Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49).
Cai H et al.
Plos One, 2012
Analysis of CYP2D6 substrate interactions by computational methods.
Ito Y et al.
Journal of Molecular Graphics & Modelling, 2008
Roles of phenylalanine at position 120 and glutamic acid at position 222 in the oxidation of chiral substrates by cytochrome P450 2D6.
Masuda K et al.
Chirality, 2006
Change in enantioselectivity in bufuralol 1''-hydroxylation by the substitution of phenylalanine-120 by alanine in cytochrome P450 2D6.
Masuda K et al.
Chirality, 2005
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