Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.G169*
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CYP2D6

NM_000106.6:p.G169*

Associated Papers

Phenotype driven molecular genetic test recommendation for diagnosing pediatric rare disorders.

Chen F et al.

Npj Digital Medicine, 2024

39572625 (PubMed )
Supplement: 41746_2024_1331_MOESM2_ESM.xlsx › Supplementary_Data_6

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone).

Matic M et al.

European Journal of Human Genetics : Ejhg, 2022

Precision Medicine into Clinical Practice: A Web-Based Tool Enables Real-Time Pharmacogenetic Assessment of Tailored Treatments in Psychiatric Disorders.

Zampatti S et al.

Journal of Personalized Medicine, 2021

Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.

Neyshaburinezhad N et al.

Journal of Personalized Medicine, 2021

34442448 (PubMed )
Supplement: jpm-11-00804-s001.zip › jpm-1270394-supplementary.pdf

Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Scott SA et al.

Clinical and Translational Science, 2021

32931151 (PubMed )
Supplement: CTS-14-204-s001.xlsx › Table_S1

Added Value of Clinical Sequencing: WGS-Based Profiling of Pharmacogenes.

Caspar SM et al.

International Journal of Molecular Sciences, 2020

32225115 (PubMed )
Supplement: ijms-21-02308-s001.zip › Caspar_et_al_Supplementary_Table_S1.xlsx › DPWG_Variants

Development of the PGx-Passport: A Panel of Actionable Germline Genetic Variants for Pre-Emptive Pharmacogenetic Testing.

van der Wouden CH et al.

Clinical Pharmacology and Therapeutics, 2019

31038729 (PubMed )
Supplement: CPT-106-866-s001.pdf

CYP2D6 allele frequencies, copy number variants, and tandems in the population of Hong Kong.

Chan W et al.

Journal of Clinical Laboratory Analysis, 2019

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation.

Goh LL et al.

Plos One, 2017

Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro.

Cai J et al.

Basic & Clinical Pharmacology & Toxicology, 2016

Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine.

Xu RA et al.

Drug Design, Development and Therapy, 2016

Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro.

Wang Z et al.

Drug Design, Development and Therapy, 2016

Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder.

Ruaño G et al.

Biomarkers in Medicine, 2013

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

[Genetic aspects of individual sensitivity to betaxolol in patients with arterial hypertension].

Minushkina LO et al.

Kardiologiia, 2008

Association of CYP2D6 and ADRB1 genes with hypotensive and antichronotropic action of betaxolol in patients with arterial hypertension.

Zateyshchikov DA et al.

Fundamental & Clinical Pharmacology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."