Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.V136M
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CYP2D6

NM_000106.6:p.V136M

Associated Papers

Leveraging in Vitro Models for Clinically Relevant Rare CYP2D6 Variants in Pharmacogenomics.

Stern S et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2024

Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations.

Twesigomwe D et al.

Clinical Pharmacology and Therapeutics, 2023

36111505 (PubMed )
Supplement: CPT-113-643-s001.pdf

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone).

Matic M et al.

European Journal of Human Genetics : Ejhg, 2022

Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Scott SA et al.

Clinical and Translational Science, 2021

32931151 (PubMed )
Supplement: CTS-14-204-s001.xlsx › Table_S1

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Zhang C et al.

Molecular Genetics & Genomic Medicine, 2019

Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics.

Ahmad T et al.

Biochemical Pharmacology, 2018

Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening.

Ng D et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017

27537706 (PubMed )
Supplement: NIHMS802548-supplement-Table_S4.pdf

Genetic polymorphisms study of pharmacogenomic VIP variants in Han ethnic of China's Shaanxi province.

Jin T et al.

Environmental Toxicology and Pharmacology, 2016

Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

Jin T et al.

Bmc Genetics, 2016

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.

Qiao W et al.

Human Mutation, 2016

Genetic Polymorphisms Analysis of Pharmacogenomic VIP Variants in Miao Ethnic Group of Southwest China.

Jin T et al.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 2015

Genetic polymorphisms in very important pharmacogenomic (VIP) variants in the Tibetan population.

Jin TB et al.

Genetics and Molecular Research : Gmr, 2015

Genetic polymorphisms of pharmacogenomic VIP variants in the Uygur population from northwestern China.

Wang L et al.

Bmc Genetics, 2015

Genetic polymorphism of pharmacogenomic VIP variants in the Deng people from the Himalayas in Southeast Tibet.

Shi X et al.

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 2015

High prevalence of CYP2D6*41 (G2988A) allele in Saudi Arabians.

Al-Dosari MS et al.

Environmental Toxicology and Pharmacology, 2013

Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population.

Wright GE et al.

Annals of Human Genetics, 2010

Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.

Matimba A et al.

Human Genomics, 2009

Determination of CYP2D6 gene alleles by the CYP450 probe array using the Affymetrix GeneChip system: comparison with sequencing results.

Ishida S et al.

Drug Metabolism and Pharmacokinetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."