Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.Q131R
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CYP2D6

NM_000106.6:p.Q131R

Associated Papers

CYP2C19 and CYP2J2 genotypes predict praziquantel plasma exposure among Ethiopian school-aged children.

Gebreyesus TD et al.

Scientific Reports, 2024

Effect of pharmacogenetic variations on praziquantel plasma concentration and safety outcomes among school children in Rwanda.

Barry A et al.

Scientific Reports, 2023

CYP2D6 and CYP3A4 variants influence the risk and outcome of COVID-19 infection among rheumatoid arthritis patients maintained on hydroxychloroquine.

Salem Hareedy M et al.

Drug Metabolism and Personalized Therapy, 2021

[CYP2D6, CYP3A5, and CYP3A4 gene polymorphism in Russian, Tatar, and Bashkir populations].

Mustafina OE et al.

Genetika, 2015

Fatal methadone toxicity: potential role of CYP3A4 genetic polymorphism.

Richards-Waugh LL et al.

Journal of Analytical Toxicology, 2014

Functional gene variants of CYP3A4.

Werk AN et al.

Clinical Pharmacology and Therapeutics, 2014

CYP450 pharmacogenetic treatment strategies for antipsychotics: a review of the evidence.

Ravyn D et al.

Schizophrenia Research, 2013

Characterization of the genetic variation present in CYP3A4 in three South African populations.

Drögemöller B et al.

Frontiers in Genetics, 2013

Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.

Sai K et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Pharmacogenetics in breast cancer therapy.

Tan SH et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation.

Zanger UM et al.

Analytical and Bioanalytical Chemistry, 2008

Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib.

Gardner ER et al.

Clinical Pharmacology and Therapeutics, 2006

Differences in CYP3A5*3 genotype distribution and combinations with other polymorphisms between Spaniards and Other Caucasian populations.

Gervasini G et al.

Therapeutic Drug Monitoring, 2005

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."