Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.F120L
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CYP2D6

NM_000106.6:p.F120L

Associated Papers

Benchmarking analysis of deleterious SNP prediction tools on CYP2D6 enzyme.

Ferreira KCDV et al.

Chemical Biology & Drug Design, 2020

Probing small-molecule binding to cytochrome P450 2D6 and 2C9: An in silico protocol for generating toxicity alerts.

Rossato G et al.

Chemmedchem, 2010

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.

Wang B et al.

Drug Metabolism Reviews, 2009

Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips.

Nakamoto K et al.

Pharmacogenetics and Genomics, 2007

Phe120 contributes to the regiospecificity of cytochrome P450 2D6: mutation leads to the formation of a novel dextromethorphan metabolite.

Flanagan JU et al.

The Biochemical Journal, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."