Associated Papers
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
The variation landscape of CYP2D6 in a multi-ethnic Asian population.
Maulana Y et al.
Scientific Reports, 2024
The impacts of natural product miltirone and the CYP2D6 pharmacogenetic phenotype on fluoxetine metabolism.
Zhang X et al.
Frontiers in Pharmacology, 2024
Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies' adaptive sampling.
Deserranno K et al.
Frontiers in Pharmacology, 2023
Effects of CYP2D6 Genetic Polymorphism and Drug Interaction on the Metabolism of Dacomitinib.
Han M et al.
Chemical Research in Toxicology, 2022
Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.
Zhang J et al.
Frontiers in Oncology, 2021
Benchmarking analysis of deleterious SNP prediction tools on CYP2D6 enzyme.
Ferreira KCDV et al.
Chemical Biology & Drug Design, 2020
Resequencing CYP2D6 gene in Indian population: CYP2D6*41 identified as the major reduced function allele.
Manoharan A et al.
Pharmacogenomics, 2019
Effect of 22 CYP2D6 variants found in the Chinese population on tolterodine metabolism in vitro.
Wang H et al.
Chemico-biological Interactions, 2017
Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro.
Fang P et al.
Drug Design, Development and Therapy, 2017
Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro.
Hu X et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2016
Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro.
Cai J et al.
Basic & Clinical Pharmacology & Toxicology, 2016
Effect of CYP2D6 variants on venlafaxine metabolism in vitro.
Zhan YY et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2016
Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine.
Xu RA et al.
Drug Design, Development and Therapy, 2016
Effects of 22 CYP2D6 Genetic Variations Newly Identified in Chinese Population on Olanzapine Metabolism in vitro.
Zhou HY et al.
Pharmacology, 2016