Varaico: Literature-Extracted Genetic Variants

Gene:CYP2D6
Variant:p.R64H
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CYP2D6

NM_000106.6:p.R64H

Associated Papers

Pharmacogenomics in cardiac therapy: Personalizing treatment for heart health.

Naderi N et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2025

RB1 aberrations predict outcomes of immune checkpoint inhibitor combination therapy in NSCLC.

Wang Q et al.

Frontiers in Oncology, 2023

37441425 (PubMed )
Supplement: Table_3.xlsx › mutations

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.

El-Boraie A et al.

Clinical and Translational Science, 2022

Study on Genotyping Polymorphism and Sequencing of N-Acetyltransferase 2 (NAT2) among Al-Ahsa Population.

Zahra MA et al.

Biomed Research International, 2020

Accurate diagnosis of mismatch repair deficiency in colorectal cancer using high-quality DNA samples from cultured stem cells.

Yamaura T et al.

Oncotarget, 2018

30680068 (PubMed )
Supplement: oncotarget-09-37534-s002.xlsx › MSI-H

NAT2 polymorphisms and risk for Parkinson's disease: a systematic review and meta-analysis.

Jiménez-Jiménez FJ et al.

Expert Opinion on Drug Metabolism & Toxicology, 2016

Genetic variability in N-acetyltransferase 2 gene determines susceptibility to childhood lymphoid or myeloid leukemia in Brazil.

Zanrosso CW et al.

Leukemia & Lymphoma, 2012

Genetic basis of toxic reactions to drugs and chemicals.

Cascorbi I

Toxicology Letters, 2006

[Restriction analysis of N-acetyltransferase 2 gene in Caucasian population of West Siberia].

Nikishina MV et al.

Genetika, 2004

Analysis of six SNPs of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype using caffeine.

Jorge-Nebert LF et al.

Pharmacogenetics, 2002

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.

Brockton N et al.

American Journal of Epidemiology, 2000

CYP2D6 genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting.

McElroy S et al.

Aaps Pharmsci, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."