Varaico: Literature-Extracted Genetic Variants

Gene:CYP2E1
Variant:p.R24M
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CYP2E1

NM_000773.4:p.R24M

Associated Papers

CYP2D6 and CYP2E1 Gene Polymorphisms and Their Influence on Chemotherapy Treatment Outcome and Toxicity in Breast Cancer Patients.

Gudur RA et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Pharmacogenetics of anxiety and depression in Alzheimer's disease.

Cacabelos R et al.

Pharmacogenomics, 2023

CYP2C8 and CYP2E1 genetic variants increase risk of tuberculosis in northwest Chinese Han population.

Xing S et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2021

Influence of Pathogenic and Metabolic Genes on the Pharmacogenetics of Mood Disorders in Alzheimer's Disease.

Cacabelos R et al.

Pharmaceuticals (basel, Switzerland), 2021

Pharmacogenetic Study of Trabectedin-Induced Severe Hepatotoxicity in Patients with Advanced Soft Tissue Sarcoma.

Maillard M et al.

Cancers, 2020

33291741 (PubMed )
Supplement: cancers-12-03647-s001.pdf

Effect of P450 Oxidoreductase Polymorphisms on the Metabolic Activities of Ten Cytochrome P450s Varied by Polymorphic CYP Genotypes in Human Liver Microsomes.

Fang Y et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2018

Polymorphisms in the human cytochrome P450 and arylamine N-acetyltransferase: susceptibility to head and neck cancers.

Khlifi R et al.

Biomed Research International, 2013

Role of cytochrome P-450 genetic polymorphisms in oral carcinogenesis.

Hernando-Rodriguez M et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012

Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis.

Kudryashov AV et al.

Bulletin of Experimental Biology and Medicine, 2011

Risk of malignant pleural mesothelioma and polymorphisms in genes involved in the genome stability and xenobiotics metabolism.

Gemignani F et al.

Mutation Research, 2009

Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity.

Neafsey P et al.

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2009

Genotyping panel for assessing response to cancer chemotherapy.

Dai Z et al.

Bmc Medical Genomics, 2008

18547414 (PubMed )
Supplement: 1755-8794-1-24-S1.xls › SNPs_selected_for_SNPlex_design

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers.

Zienolddiny S et al.

Carcinogenesis, 2008

Regulatory polymorphisms and their contribution to interindividual differences in the expression of enzymes influencing drug and toxicant disposition.

Hines RN et al.

Drug Metabolism Reviews, 2008

Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes.

Gemignani F et al.

Carcinogenesis, 2007

Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology.

Ferreira PM et al.

European Journal of Clinical Pharmacology, 2006

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.

Landi S et al.

Pharmacogenetics and Genomics, 2005

A database of single-nucleotide polymorphisms and a genotyping microarray for genetic epidemiology of lung cancer.

Landi S et al.

Experimental Lung Research, 2005

Association of cytochrome P450 2E1 polymorphisms and head and neck squamous cell cancer.

Neuhaus T et al.

Toxicology Letters, 2004

Suppression of cytochrome P450 2E1 promoter activity by interferon-gamma and loss of response due to the -71G>T nucleotide polymorphism of the CYP2E1*7B allele.

Qiu LO et al.

The Journal of Pharmacology and Experimental Therapeutics, 2004

Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes.

Thier R et al.

International Journal of Hygiene and Environmental Health, 2003

The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine.

Bolt HM et al.

International Archives of Occupational and Environmental Health, 2003

Association of CYP1B1 codon 432 mutant allele in head and neck squamous cell cancer is reflected by somatic mutations of p53 in tumor tissue.

Ko Y et al.

Cancer Research, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."