Associated Papers
Comprehensive functional characterization of rare and known CYP2E1 allelic variants identified in a Japanese population.
Ohmori Y et al.
Biochemical Pharmacology, 2025
Genetic and epigenetic determinants of fetal alcohol spectrum disorders: Toward a precision medicine approach.
Sessa F et al.
Experimental and Molecular Pathology, 2025
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
Analysis of alcohol-metabolizing enzymes genetic variants and RAR/RXR expression in patients diagnosed with fetal alcohol syndrome: a case-control study.
Vieiros M et al.
Bmc Genomics, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.
Neyshaburinezhad N et al.
Journal of Personalized Medicine, 2021
Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing.
Nanki Y et al.
Scientific Reports, 2020
Functional characterization of the chlorzoxazone 6-hydroxylation activity of human cytochrome P450 2E1 allelic variants in Han Chinese.
Wang T et al.
Peerj, 2020
Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population.
Zhu L et al.
Medicine, 2018
Characterization of ADME gene variation in 21 populations by exome sequencing.
Hovelson DH et al.
Pharmacogenetics and Genomics, 2017
Human cytochrome P450 2E1 mutations that alter mitochondrial targeting efficiency and susceptibility to ethanol-induced toxicity in cellular models.
Bansal S et al.
The Journal of Biological Chemistry, 2013
Relevance of CYP2E1 to non-alcoholic fatty liver disease.
Daly AK
Sub-cellular Biochemistry, 2013
CYP2E1*5B, CYP2E1*6, CYP2E1*7B, CYP2E1*2, and CYP2E1*3 allele frequencies in iranian populations.
Shahriary GM et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2012
Phenotype prediction of deleterious nonsynonymous single nucleotide polymorphisms in human alcohol metabolism-related genes: a bioinformatics study.
Wang LL et al.
Alcohol (fayetteville, N.y.), 2010
Functional characterization of human cytochrome P4502E1 allelic variants: in vitro metabolism of benzene and toluene by recombinant enzymes expressed in yeast cells.
Hanioka N et al.
Archives of Toxicology, 2010
Variability in ethanol biodisposition in whites is modulated by polymorphisms in the ADH1B and ADH1C genes.
Martínez C et al.
Hepatology (baltimore, Md.), 2010
Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity.
Neafsey P et al.
Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2009
[Cancer pharmacogenetics: study of genetically determined variations on cancer susceptibility due to xenobiotic exposure].
Quiñones L et al.
Revista Medica De Chile, 2006
Genetic basis of toxic reactions to drugs and chemicals.
Cascorbi I
Toxicology Letters, 2006
The human genome project and novel aspects of cytochrome P450 research.
Ingelman-Sundberg M
Toxicology and Applied Pharmacology, 2005
Cytochrome P450 gene polymorphisms and risk of low birth weight.
Chen D et al.
Genetic Epidemiology, 2005
[Associations of genetic polymorphisms in the EPHX1 gene and the GSTT1 gene with low birth weight in neonates].
Liang HY et al.
Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences, 2005
Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms.
Ingelman-Sundberg M
Naunyn-schmiedeberg's Archives of Pharmacology, 2004
Functional characterization of three human cytochrome p450 2E1 variants with amino acid substitutions.
Hanioka N et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2003
The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine.
Bolt HM et al.
International Archives of Occupational and Environmental Health, 2003
Pharmacogenetics of the major polymorphic metabolizing enzymes.
Daly AK
Fundamental & Clinical Pharmacology, 2003
Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes.
Ingelman-Sundberg M
Mutation Research, 2001
Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorder.
Harada S et al.
Alcoholism, Clinical and Experimental Research, 2001
Mutations in the exons and exon-intron junction regions of human cytochrome P-4502E1 gene and alcoholism.
Itoga S et al.
Alcoholism, Clinical and Experimental Research, 1999
Functional consequences of polymorphism of xenobiotic metabolising enzymes.
Ingelman-Sundberg M
Toxicology Letters, 1998
[Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions].
Itoga S et al.
Nihon Arukoru Yakubutsu Igakkai Zasshi = Japanese Journal of Alcohol Studies & Drug Dependence, 1998
Genetic polymorphism of human CYP2E1: characterization of two variant alleles.
Hu Y et al.
Molecular Pharmacology, 1997