Associated Papers
Comprehensive functional characterization of rare and known CYP2E1 allelic variants identified in a Japanese population.
Ohmori Y et al.
Biochemical Pharmacology, 2025
Genetic and epigenetic determinants of fetal alcohol spectrum disorders: Toward a precision medicine approach.
Sessa F et al.
Experimental and Molecular Pathology, 2025
Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.
Twesigomwe D et al.
Scientific Reports, 2025
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
Characterization of NAT, GST, and CYP2E1 Genetic Variation in Sub-Saharan African Populations: Implications for Treatment of Tuberculosis and Other Diseases.
Malinga TVB et al.
Clinical Pharmacology and Therapeutics, 2025
Analysis of alcohol-metabolizing enzymes genetic variants and RAR/RXR expression in patients diagnosed with fetal alcohol syndrome: a case-control study.
Vieiros M et al.
Bmc Genomics, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies' adaptive sampling.
Deserranno K et al.
Frontiers in Pharmacology, 2023
Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.
Neyshaburinezhad N et al.
Journal of Personalized Medicine, 2021
Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population.
Zhu L et al.
Medicine, 2018
Novel human genome variants associated with alcohol use disorders identified in a Lithuanian cohort.
Baronas K et al.
Acta Medica Lituanic, 2018
Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis.
Skarp S et al.
Plos One, 2018
Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers.
Court MH et al.
The Journal of Pharmacology and Experimental Therapeutics, 2017
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Functional PstI/RsaI polymorphisms in the CYP2E1 gene among south Indian populations.
Lakkakula S et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2013
Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy.
Preissner SC et al.
Plos One, 2013
A comparison of Val81Met and other polymorphisms of alcohol metabolising genes in patients and controls in Northern Spain.
Celorrio D et al.
Alcohol (fayetteville, N.y.), 2012
Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians.
Balaji L et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2011
Phenotype prediction of deleterious nonsynonymous single nucleotide polymorphisms in human alcohol metabolism-related genes: a bioinformatics study.
Wang LL et al.
Alcohol (fayetteville, N.y.), 2010
Functional characterization of human cytochrome P4502E1 allelic variants: in vitro metabolism of benzene and toluene by recombinant enzymes expressed in yeast cells.
Hanioka N et al.
Archives of Toxicology, 2010
Biomarkers of human exposure to acrylamide and relation to polymorphisms in metabolizing genes.
Duale N et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology, 2009
Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity.
Neafsey P et al.
Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2009
Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene.
Lee MY et al.
The Pharmacogenomics Journal, 2008
[Cancer pharmacogenetics: study of genetically determined variations on cancer susceptibility due to xenobiotic exposure].
Quiñones L et al.
Revista Medica De Chile, 2006
The human genome project and novel aspects of cytochrome P450 research.
Ingelman-Sundberg M
Toxicology and Applied Pharmacology, 2005
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005
Functional characterization of three human cytochrome p450 2E1 variants with amino acid substitutions.
Hanioka N et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2003
The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine.
Bolt HM et al.
International Archives of Occupational and Environmental Health, 2003
Detection and characterization of novel polymorphisms in the CYP2E1 gene.
Fairbrother KS et al.
Pharmacogenetics, 1998