Varaico: Literature-Extracted Genetic Variants

Gene:CYP2J2
Variant:p.P351L
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CYP2J2

NM_000775.4:p.P351L

Associated Papers

Functional Characterization of Allelic Variations of Human Cytochrome P450 2C8 (V181I, I244V, I331T, and L361F).

Lee YB et al.

International Journal of Molecular Sciences, 2023

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.

Chamboko CR et al.

International Journal of Molecular Sciences, 2023

36834793 (PubMed )
Supplement: ijms-24-03383-s001.zip › ijms-2130595-supplementary.pdf

Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro.

Zou LL et al.

Frontiers in Pharmacology, 2023

Terfenadine metabolism of human cytochrome P450 2J2 containing genetic variations (G312R, P351L and P115L).

Jeong D et al.

Drug Metabolism and Pharmacokinetics, 2018

Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity.

Lee SS et al.

Pharmacogenetics and Genomics, 2005

Genetic polymorphisms, drug metabolism and drug concentrations.

Shenfield GM

The Clinical Biochemist. Reviews, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."