Varaico: Literature-Extracted Genetic Variants

Gene:CYP2J2
Variant:p.V26F
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CYP2J2

NM_000775.4:p.V26F

Associated Papers

Relevance of selected pharmacogenetic polymorphisms to bleeding and thromboembolic risks in Chinese patients taking direct-acting oral anticoagulants.

Wang D et al.

British Journal of Clinical Pharmacology, 2025

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro.

Zou LL et al.

Frontiers in Pharmacology, 2023

Effect of ABCB1 gene variants on rivaroxaban pharmacokinetic and hemorrhage events occurring in patients with non-valvular atrial fibrillation.

Zhang D et al.

Biopharmaceutics & Drug Disposition, 2022

Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients.

Campos-Staffico AM et al.

Frontiers in Pharmacology, 2022

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

Associations between CYP2J2 (-76G>T) rs890293 polymorphism and age-related macular degeneration.

Liutkeviciene R et al.

Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2020

CYP3A5*3 and CYP2C8*3 variants influence exposure and clinical outcomes of tacrolimus-based therapy.

Genvigir FDV et al.

Pharmacogenomics, 2020

Activity and mRNA expression levels of selected cytochromes P450 in various sections of the human small intestine.

Clermont V et al.

British Journal of Clinical Pharmacology, 2019

A comprehensive study revealed SNP-SNP interactions and a sex-dependent relationship between polymorphisms of the CYP2J2 gene and hypertension risk.

Polonikov AV et al.

Hypertension Research : Official Journal of the Japanese Society of Hypertension, 2019

Genetic polymorphisms of CYP2S1, CYP2J2 and CYP2R1 genes in three Chinese populations: Han, Tibetan and Uighur.

Kang X et al.

Pharmacogenomics, 2018

Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation.

Yu M et al.

Current Drug Metabolism, 2018

Meta-analysis of the association of the CYP2J2 G-50T polymorphism with coronary artery disease.

Chen J et al.

Oncotarget, 2017

Influence of ABCC2, CYP2C8, and CYP2J2 Polymorphisms on Tacrolimus and Mycophenolate Sodium-Based Treatment in Brazilian Kidney Transplant Recipients.

Genvigir FDV et al.

Pharmacotherapy, 2017

The contribution of CYP2C gene subfamily involved in epoxygenase pathway of arachidonic acids metabolism to hypertension susceptibility in Russian population.

Polonikov A et al.

Clinical and Experimental Hypertension (new York, N.y. : 1993), 2017

Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect.

Ing Lorenzini K et al.

Frontiers in Pharmacology, 2016

Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.

Zanger UM et al.

Pharmacology & Therapeutics, 2013

Polymorphisms of cytochrome p450 genes in three ethnic groups from Russia.

Korytina G et al.

Balkan Medical Journal, 2012

[Polymorphic markers of the CYP1B1 (4326C > G), CYP2F1 (c.14_15insC), CYP2J2 (-76G > T), and CYP2S1 (13106C > T and 13255A > G) genes and genetic predisposition to chronic respiratory diseases induced by smoking and occupational factors].

Akhmadishina LA et al.

Genetika, 2011

Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations.

Yamazaki H et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2006

Genetic polymorphisms, drug metabolism and drug concentrations.

Shenfield GM

The Clinical Biochemist. Reviews, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."