Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.P488fs
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CYP3A4

NM_017460.6:p.P488fs

Associated Papers

Activation/Inactivation of Anticancer Drugs by CYP3A4: Influencing Factors for Personalized Cancer Therapy.

Wang F et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table2.xlsx › Hoja1

EXPLORATORY ANALYSIS OF RARE AND NOVEL VARIANTS IN MEXICAN PATIENTS DIAGNOSED WITH SCHIZOPHRENIA AND DEMENTIA.

Martínez-Magaña JJ et al.

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, 2019

High frequency and founder effect of the CYP3A4*20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme.

Apellániz-Ruiz M et al.

The Pharmacogenomics Journal, 2015

Whole-exome sequencing reveals defective CYP3A4 variants predictive of paclitaxel dose-limiting neuropathy.

Apellániz-Ruiz M et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."