Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.E417K
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CYP3A4

NM_017460.6:p.E417K

Associated Papers

ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?

Bruckmueller H et al.

Expert Opinion on Drug Metabolism & Toxicology, 2021

Effect of MRP2 and MRP3 Polymorphisms on Anastrozole Glucuronidation and MRP2 and MRP3 Gene Expression in Normal Liver Samples.

Edavana VK et al.

International Journal of Cancer Research and Molecular Mechanisms, 2015

Multidrug resistance-associated protein 2 (MRP2/ABCC2) haplotypes significantly affect the pharmacokinetics of tacrolimus in kidney transplant recipients.

Ogasawara K et al.

Clinical Pharmacokinetics, 2013

Effect of ABCC2 (MRP2) transport function on erythromycin metabolism.

Franke RM et al.

Clinical Pharmacology and Therapeutics, 2011

Analysis of pharmacogenetic traits in two distinct South African populations.

Ikediobi O et al.

Human Genomics, 2011

Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients.

Naesens M et al.

Transplantation, 2006

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.

Ieiri I et al.

Expert Opinion on Drug Metabolism & Toxicology, 2006

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.

Bosch TM et al.

Molecular Diagnosis & Therapy, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."