Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.A370V
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CYP3A4

NM_017460.6:p.A370V

Associated Papers

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6β-Hydroxylation.

Kumondai M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Guttman Y et al.

Frontiers in Genetics, 2019

30941162 (PubMed )
Supplement: Table_2.xlsx › FrontiersEast_Asian

Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations.

Müller CS et al.

Biochemistry, 2015

Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis.

He YA et al.

Biochemistry, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."