Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.E308G
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CYP3A4

NM_017460.6:p.E308G

Associated Papers

Exploring Trimethylaminuria: Genetics and Molecular Mechanisms, Epidemiology, and Emerging Therapeutic Strategies.

Sidoti A et al.

Biology, 2024

Flavin-containing monooxygenases: mutations, disease and drug response.

Phillips IR et al.

Trends in Pharmacological Sciences, 2008

Flavin-containing monooxygenase 3 and human disease.

Motika MS et al.

Expert Opinion on Drug Metabolism & Toxicology, 2007

Haplotype frequency distribution and linkage disequilibrium analysis of single nucleotide polymorphisms at the human FMO3 gene locus.

Hao DC et al.

Biochemical Genetics, 2006

The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development.

Cashman JR

Drug Discovery Today, 2004

Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation.

Cashman JR et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2002

Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.

Störmer E et al.

British Journal of Clinical Pharmacology, 2000

Allele and genotype frequencies of polymorphic FMO3 gene in two genetically distinct populations.

Hao D et al.

Cell Biochemistry and Function, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."