Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.F219S
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CYP3A4

NM_017460.6:p.F219S

Associated Papers

The impacts of natural product miltirone and the CYP2D6 pharmacogenetic phenotype on fluoxetine metabolism.

Zhang X et al.

Frontiers in Pharmacology, 2024

Effects of CYP2D6 Genetic Polymorphism and Drug Interaction on the Metabolism of Dacomitinib.

Han M et al.

Chemical Research in Toxicology, 2022

In vitro assessment of 24 CYP2D6 allelic isoforms on the metabolism of methadone.

Su Y et al.

Drug Testing and Analysis, 2017

Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro.

Fang P et al.

Drug Design, Development and Therapy, 2017

Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro.

Hu X et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2016

Functional characterization of 22 novel CYP2D6 variants for the metabolism of Tamoxifen.

Hu XX et al.

The Journal of Pharmacy and Pharmacology, 2016

Effect of CYP2D6 genetic polymorphism on the metabolism of citalopram in vitro.

Hu XX et al.

Drug Metabolism and Pharmacokinetics, 2016

Effect of CYP2D6 variants on venlafaxine metabolism in vitro.

Zhan YY et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2016

Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine.

Xu RA et al.

Drug Design, Development and Therapy, 2016

Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro.

Wang Z et al.

Drug Design, Development and Therapy, 2016

Effects of 24 CYP2D6 Variants Found in the Chinese Population on the Metabolism of Risperidone.

Wang ZH et al.

Pharmacology, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."