Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.D174H
Back to variants list

CYP3A4

NM_017460.6:p.D174H

Associated Papers

Effects of CYP3A4 Variants on Methadone Metabolism In Vitro.

Wang CC et al.

Biomedical Chromatography : Bmc, 2025

Identification and Functional Assessment of Eight CYP3A4 Allelic Variants *39-*46 Detected in the Chinese Han Population.

Qi Y et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2024

The effect of gene polymorphism on ticagrelor metabolism: an in vitro study of 22 CYP3A4 variants in Chinese Han population.

Hu X et al.

Peerj, 2024

Characterization of Reference Materials for CYP3A4 and CYP3A5: A (GeT-RM) Collaborative Project.

Gaedigk A et al.

The Journal of Molecular Diagnostics : Jmd, 2023

CYP3A4 and CYP3A5 Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, and Pharmacogenomics Knowledgebase.

Pratt VM et al.

The Journal of Molecular Diagnostics : Jmd, 2023

Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro.

Liu Q et al.

Fundamental & Clinical Pharmacology, 2022

Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Zhai Q et al.

Frontiers in Pharmacology, 2022

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6β-Hydroxylation.

Kumondai M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

Functional characterization of 21 CYP3A4 variants on amiodarone metabolism in vitro.

Yang CC et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2019

Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Guttman Y et al.

Frontiers in Genetics, 2019

30941162 (PubMed )
Supplement: Table_2.xlsx › FrontiersAfrican

Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro.

Zhou XY et al.

Frontiers in Pharmacology, 2019

Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro.

Fang P et al.

Drug Design, Development and Therapy, 2017

Functional gene variants of CYP3A4.

Werk AN et al.

Clinical Pharmacology and Therapeutics, 2014

The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.

Wang D et al.

Journal of Personalized Medicine, 2012

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients.

Sai K et al.

Cancer Chemotherapy and Pharmacology, 2008

Toward individualized treatment: prediction of anticancer drug disposition and toxicity with pharmacogenetics.

Deeken JF et al.

Anti-cancer Drugs, 2007

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."