Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.S139N
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CYP3A4

NM_017460.6:p.S139N

Associated Papers

Influence of CYP2C8*3 and ABCG2 C421A genetic polymorphisms on trough concentration and molecular response of imatinib in Egyptian patients with chronic myeloid leukemia.

Mangoura SA et al.

Cancer Chemotherapy and Pharmacology, 2024

Effects of functional CYP2C8,CYP2C9,CYP3A5,and ABCB1 genetic variants on the pharmacokinetics of insulin sensitizer pioglitazone in Chinese Han individuals.

Yin SJ et al.

Pharmacogenetics and Genomics, 2017

Genetic polymorphisms of CYP2C8 in the Czech Republic.

Pechandova K et al.

Genetic Testing and Molecular Biomarkers, 2012

Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients.

Seredina TA et al.

Bmc Medical Genetics, 2012

Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer.

Gréen H et al.

Basic & Clinical Pharmacology & Toxicology, 2009

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?

Singh V et al.

Cancer Investigation, 2008

Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa.

Parikh S et al.

Clinical Pharmacology and Therapeutics, 2007

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics.

Niemi M et al.

Clinical Pharmacology and Therapeutics, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."