Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.R130*
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CYP3A4

NM_017460.6:p.R130*

Associated Papers

CYP3A4 activity variations can lead to stratified metabolism of abemaciclib.

Xu XY et al.

International Journal of Biological Macromolecules, 2025

Effects of CYP3A4 Variants on Methadone Metabolism In Vitro.

Wang CC et al.

Biomedical Chromatography : Bmc, 2025

The effect of gene polymorphism on ticagrelor metabolism: an in vitro study of 22 CYP3A4 variants in Chinese Han population.

Hu X et al.

Peerj, 2024

CYP3A4 and CYP3A5 Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, and Pharmacogenomics Knowledgebase.

Pratt VM et al.

The Journal of Molecular Diagnostics : Jmd, 2023

Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Zhai Q et al.

Frontiers in Pharmacology, 2022

Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro.

Zhou XY et al.

Frontiers in Pharmacology, 2019

Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro.

Fang P et al.

Drug Design, Development and Therapy, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."