Associated Papers
Interaction of cytochrome P450 3A4 with cannabinoids and the drug darifenacin.
Sevrioukova IF
The Journal of Biological Chemistry, 2025
Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations.
Müller CS et al.
Biochemistry, 2015
Dissecting cytochrome P450 3A4-ligand interactions using ritonavir analogues.
Sevrioukova IF et al.
Biochemistry, 2013
Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneity.
Kumar S et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2005
CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis.
Gupta RP et al.
The Journal of Clinical Endocrinology and Metabolism, 2005
The importance of SRS-1 residues in catalytic specificity of human cytochrome P450 3A4.
Roussel F et al.
Archives of Biochemistry and Biophysics, 2000
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