Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.L22F
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CYP3A4

NM_017460.6:p.L22F

Associated Papers

Association of CYP2B6 and OPRM1 Genotypes with Methadone Dose Requirements and Serum Concentrations in a Vietnamese Cohorts.

Nguyen QG et al.

Balkan Journal of Medical Genetics : Bjmg, 2025

Genetic Polymorphisms in Cytochrome P450 Enzymes Involved in Vitamin D Metabolism and the Vitamin D Receptor: Their Clinical Relevance.

Jarrar Y et al.

Journal of Personalized Medicine, 2025

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6β-Hydroxylation.

Kumondai M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4.

Sevrioukova IF

Biochemistry, 2017

CYP2B6 haplotype and biological factors responsible for hepatotoxicity in HIV-infected patients receiving efavirenz-based antiretroviral therapy.

Manosuthi W et al.

International Journal of Antimicrobial Agents, 2014

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?

Singh V et al.

Cancer Investigation, 2008

Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese.

Guan S et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2006

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

Tsuchiya K et al.

Biochemical and Biophysical Research Communications, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."