Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A4
Variant:p.A8A
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CYP3A4

NM_017460.6:p.A8A

Associated Papers

Effects of ABCG2 421C > A genetic polymorphism on the pharmacokinetics of rivaroxaban in healthy Chinese subjects.

Guo L et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2025

ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?

Bruckmueller H et al.

Expert Opinion on Drug Metabolism & Toxicology, 2021

Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.

Arrigoni E et al.

International Journal of Molecular Sciences, 2017

Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.

Chen S et al.

Drug Metabolism Reviews, 2016

Effect of MRP2 and MRP3 Polymorphisms on Anastrozole Glucuronidation and MRP2 and MRP3 Gene Expression in Normal Liver Samples.

Edavana VK et al.

International Journal of Cancer Research and Molecular Mechanisms, 2015

Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy.

Becker ML et al.

The Pharmacogenomics Journal, 2013

Association of CYP3A4/5, ABCB1 and ABCC2 polymorphisms and clinical outcomes of Thai breast cancer patients treated with tamoxifen.

Sensorn I et al.

Pharmacogenomics and Personalized Medicine, 2013

Human pregnane X receptor genotype of the donor but not of the recipient is a risk factor for delayed graft function after renal transplantation.

Hauser IA et al.

Clinical Pharmacology and Therapeutics, 2012

Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.

Sai K et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Effect of ABCC2 (MRP2) transport function on erythromycin metabolism.

Franke RM et al.

Clinical Pharmacology and Therapeutics, 2011

Analysis of pharmacogenetic traits in two distinct South African populations.

Ikediobi O et al.

Human Genomics, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."