Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A43
Variant:p.M445T
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CYP3A43

NM_057095.3:p.M445T

Associated Papers

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.

Ekhart C et al.

British Journal of Clinical Pharmacology, 2009

CYP450 pharmacogenetics for personalizing cancer therapy.

van Schaik RH

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 2008

Recombinant CYP3A4*17 is defective in metabolizing the hypertensive drug nifedipine, and the CYP3A4*17 allele may occur on the same chromosome as CYP3A5*3, representing a new putative defective CYP3A haplotype.

Lee SJ et al.

The Journal of Pharmacology and Experimental Therapeutics, 2005

An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore.

Chowbay B et al.

Drug Metabolism Reviews, 2005

Identification and functional characterization of eight CYP3A4 protein variants.

Eiselt R et al.

Pharmacogenetics, 2001

Sequence diversity and haplotype structure at the human CYP3A cluster.

Thompson EE et al.

The Pharmacogenomics Journal, 0

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