Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.P389S
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CYP3A5

NM_000777.5:p.P389S

Associated Papers

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Abdelazim AA et al.

Scientific Reports, 2025

Cytochrome P450 3A5 polymorphism affects the metabolism of sorafenib and its toxicity for hepatocellular carcinoma cells in vitro.

Song HY et al.

Human & Experimental Toxicology, 2021

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6β-Hydroxylation.

Kumondai M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 2A6 in a Tibetan Chinese population.

Xia R et al.

International Journal of Clinical and Experimental Pathology, 2018

Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 3A5 in a Uyghur Chinese population.

Chen Z et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2016

Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes.

Lee JS et al.

The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2013

Cytochrome P450 3A5 polymorphism affects the metabolism of sorafenib and its toxicity for hepatocellular carcinoma cells in vitro.

Song HY et al.

Human & Experimental Toxicology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."