Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.N262S
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CYP3A5

NM_000777.5:p.N262S

Associated Papers

Methadone metabolism and cytochrome P450 polymorphisms: a systematic review and meta-analysis.

Eum S et al.

Expert Opinion on Drug Metabolism & Toxicology, 2024

Severe and prolonged cyclophosphamide-induced hepatotoxicity in a breast cancer patient carrying a CYP2B6*7 variant.

Ming Z et al.

Pharmacogenomics, 2019

Gene polymorphisms and contents of cytochrome P450s have only limited effects on metabolic activities in human liver microsomes.

Gao N et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2016

Cytochrome P450 variations in different ethnic populations.

McGraw J et al.

Expert Opinion on Drug Metabolism & Toxicology, 2012

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response.

Fonseca F et al.

Plos One, 2011

Haplotype structure and allele frequencies of CYP2B6 in Spaniards and Central Americans.

Arenaz I et al.

Fundamental & Clinical Pharmacology, 2010

Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam.

Veiga MI et al.

European Journal of Clinical Pharmacology, 2009

Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects.

Robertson SM et al.

Journal of Acquired Immune Deficiency Syndromes (1999), 2008

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?

Singh V et al.

Cancer Investigation, 2008

Pharmacogenetics in HIV therapy.

Rodríguez-Nóvoa S et al.

Aids Reviews, 0

Overview of the pharmacogenetics of HIV therapy.

Rodríguez-Nóvoa S et al.

The Pharmacogenomics Journal, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."