Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.F210L
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CYP3A5

NM_000777.5:p.F210L

Associated Papers

Active-site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4.

Hsu MH et al.

The Journal of Biological Chemistry, 2019

Cytochrome P450 3A5 plays a prominent role in the oxidative metabolism of the anti-human immunodeficiency virus drug maraviroc.

Lu Y et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."