Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.T185S
Back to variants list

CYP3A5

NM_000777.5:p.T185S

Associated Papers

Differential metabolism of citalopram by 21 CYP3A4 variants: An in vitro experiment.

Wang P et al.

Journal of Psychopharmacology (oxford, England), 2025

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Abdelazim AA et al.

Scientific Reports, 2025

Effects of CYP3A4 Variants on Methadone Metabolism In Vitro.

Wang CC et al.

Biomedical Chromatography : Bmc, 2025

Characterization of Reference Materials for CYP3A4 and CYP3A5: A (GeT-RM) Collaborative Project.

Gaedigk A et al.

The Journal of Molecular Diagnostics : Jmd, 2023

Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function.

Fohner AE et al.

Clinical and Translational Science, 2021

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Functional gene variants of CYP3A4.

Werk AN et al.

Clinical Pharmacology and Therapeutics, 2014

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.

Sai K et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients.

Sai K et al.

Cancer Chemotherapy and Pharmacology, 2008

Impact of the haplotype CYP3A4*16B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer.

Nakajima Y et al.

Clinical Pharmacology and Therapeutics, 2006

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."