Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.T185S
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CYP3A5

NM_000777.5:p.T185S

Associated Papers

Differential metabolism of citalopram by 21 CYP3A4 variants: An in vitro experiment.

Wang P et al.

Journal of Psychopharmacology (oxford, England), 2025

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Abdelazim AA et al.

Scientific Reports, 2025

Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function.

Fohner AE et al.

Clinical and Translational Science, 2021

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

Impact of the haplotype CYP3A4*16B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer.

Nakajima Y et al.

Clinical Pharmacology and Therapeutics, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."