Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.D174H
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CYP3A5

NM_000777.5:p.D174H

Associated Papers

Differential metabolism of citalopram by 21 CYP3A4 variants: An in vitro experiment.

Wang P et al.

Journal of Psychopharmacology (oxford, England), 2025

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Abdelazim AA et al.

Scientific Reports, 2025

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Contrasting exome constancy and regulatory region variation in the gene encoding CYP3A4: an examination of the extent and potential implications.

Creemer OJ et al.

Pharmacogenetics and Genomics, 2016

Functional gene variants of CYP3A4.

Werk AN et al.

Clinical Pharmacology and Therapeutics, 2014

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis.

Gupta RP et al.

The Journal of Clinical Endocrinology and Metabolism, 2005

Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

Fukushima-Uesaka H et al.

Human Mutation, 2004

Identification and functional characterization of eight CYP3A4 protein variants.

Eiselt R et al.

Pharmacogenetics, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."