Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.I118V
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CYP3A5

NM_000777.5:p.I118V

Associated Papers

Differential metabolism of citalopram by 21 CYP3A4 variants: An in vitro experiment.

Wang P et al.

Journal of Psychopharmacology (oxford, England), 2025

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Abdelazim AA et al.

Scientific Reports, 2025

Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro.

Zhou XY et al.

Frontiers in Pharmacology, 2019

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Gene polymorphisms and contents of cytochrome P450s have only limited effects on metabolic activities in human liver microsomes.

Gao N et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2016

Functional gene variants of CYP3A4.

Werk AN et al.

Clinical Pharmacology and Therapeutics, 2014

Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes.

Lee JS et al.

The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2013

CYP3A and ABCB1 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of tacrolimus and its metabolites (M-I and M-III).

Yoon SH et al.

Transplantation, 2013

Impact of cytochrome P450 3A and ATP-binding cassette subfamily B member 1 polymorphisms on tacrolimus dose-adjusted trough concentrations among Korean renal transplant recipients.

Cho JH et al.

Transplantation Proceedings, 2012

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

Pharmacogenomics of statin responsiveness.

Kajinami K et al.

The American Journal of Cardiology, 2005

Statin response and pharmacokinetics variants.

Kajinami K et al.

Expert Opinion on Pharmacotherapy, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."