Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.R28C
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CYP3A5

NM_000777.5:p.R28C

Associated Papers

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Abdelazim AA et al.

Scientific Reports, 2025

Individualized tacrolimus therapy: Insights from CYP3A5 polymorphisms and intestinal metabolism.

Mishima M et al.

Clinical Case Reports, 2024

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.

Chamboko CR et al.

International Journal of Molecular Sciences, 2023

36834793 (PubMed )
Supplement: ijms-24-03383-s001.zip › ijms-2130595-supplementary.pdf

PharmVar GeneFocus: CYP3A5.

Rodriguez-Antona C et al.

Clinical Pharmacology and Therapeutics, 2022

Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Goljan E et al.

Plos One, 2022

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

Precision Medicine into Clinical Practice: A Web-Based Tool Enables Real-Time Pharmacogenetic Assessment of Tailored Treatments in Psychiatric Disorders.

Zampatti S et al.

Journal of Personalized Medicine, 2021

Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.

Neyshaburinezhad N et al.

Journal of Personalized Medicine, 2021

34442448 (PubMed )
Supplement: jpm-11-00804-s001.zip › jpm-1270394-supplementary.pdf

Single Nucleotide Polymorphism Induces Divergent Dynamic Patterns in CYP3A5: A Microsecond Scale Biomolecular Simulation of Variants Identified in Sub-Saharan African Populations.

Othman H et al.

International Journal of Molecular Sciences, 2021

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.

Mukonzo JK et al.

British Journal of Clinical Pharmacology, 2009

Pharmacogenomics of CYP3A: considerations for HIV treatment.

Lakhman SS et al.

Pharmacogenomics, 2009

Polymorphism of antimalaria drug metabolizing, nuclear receptor, and drug transport genes among malaria patients in Zanzibar, East Africa.

Ferreira PE et al.

Therapeutic Drug Monitoring, 2008

Significance of the minor cytochrome P450 3A isoforms.

Daly AK

Clinical Pharmacokinetics, 2006

Increased levels of aflatoxin-albumin adducts are associated with CYP3A5 polymorphisms in The Gambia, West Africa.

Wojnowski L et al.

Pharmacogenetics, 2004

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups.

Lee SJ et al.

Pharmacogenetics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."