Varaico: Literature-Extracted Genetic Variants

Gene:CYP3A5
Variant:p.T11insFs
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CYP3A5

NM_000777.5:p.T11insFs

Associated Papers

Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations.

Simba H et al.

Frontiers in Genetics, 2019

Association between CYP3A5 polymorphisms and blood pressure in kidney transplant recipients receiving calcineurin inhibitors.

Ferraresso M et al.

Clinical and Experimental Hypertension (new York, N.y. : 1993), 2011

Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam.

Veiga MI et al.

European Journal of Clinical Pharmacology, 2009

Polymorphism of antimalaria drug metabolizing, nuclear receptor, and drug transport genes among malaria patients in Zanzibar, East Africa.

Ferreira PE et al.

Therapeutic Drug Monitoring, 2008

Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam.

Kharasch ED et al.

Clinical Pharmacology and Therapeutics, 2007

CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir.

Josephson F et al.

Clinical Pharmacology and Therapeutics, 2007

Toward individualized treatment: prediction of anticancer drug disposition and toxicity with pharmacogenetics.

Deeken JF et al.

Anti-cancer Drugs, 2007

Ethnic differences in the distribution of CYP3A5 gene polymorphisms.

Quaranta S et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2006

Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition.

Lee SJ et al.

Journal of Clinical Pharmacology, 2006

Significance of the minor cytochrome P450 3A isoforms.

Daly AK

Clinical Pharmacokinetics, 2006

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.

Bosch TM et al.

Clinical Pharmacokinetics, 2006

CYP3A5 genotypes and risk of oesophageal cancer in two South African populations.

Dandara C et al.

Cancer Letters, 2005

Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.

He P et al.

Clinical Pharmacology and Therapeutics, 2005

An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore.

Chowbay B et al.

Drug Metabolism Reviews, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."