Associated Papers
Integration of metabolomic and genetic data reveals novel variants underpinning the human metabolome: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Krishnan M et al.
Medrxiv : the Preprint Server for Health Sciences, 2026
Comprehensive pharmacogenomics profiling of the Serbian population.
Jelovac M et al.
Frontiers in Pharmacology, 2025
Pharmacogenetic analysis of structural variation in the 1000 genomes project using whole genome sequences.
Sherman CA et al.
Scientific Reports, 2024
APF2: an improved ensemble method for pharmacogenomic variant effect prediction.
Zhou Y et al.
The Pharmacogenomics Journal, 2024
Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.
Álvarez-Prado ÁF et al.
Cell Reports. Medicine, 2023
Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy.
Mota-Zamorano S et al.
Journal of Clinical Medicine, 2021
Vascular contributions to cognitive impairment and dementia: the emerging role of 20-HETE.
Gonzalez-Fernandez E et al.
Clinical Science (london, England : 1979), 2021
Whole genome mapping and identification of single nucleotide polymorphisms of four Bangladeshi individuals and their functional significance.
Khan S et al.
Bmc Research Notes, 2021
Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.
Fontana D et al.
Hemasphere, 2020
Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression.
Singh R et al.
Plos One, 2020
An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Zhou Y et al.
The Pharmacogenomics Journal, 2019
X-linked ADGRG2 mutation and obstructive azoospermia in a large Pakistani family.
Khan MJ et al.
Scientific Reports, 2018
Biochemical analysis of recombinant CYP4A11 allelic variant enzymes: W126R, K276T and S353G.
Han S et al.
Drug Metabolism and Pharmacokinetics, 2016
Risk factors for post-transplant diabetes mellitus in renal transplant: Role of genetic variability in the CYP450-mediated arachidonic acid metabolism.
Gervasini G et al.
Molecular and Cellular Endocrinology, 2016
Polymorphisms in CYP-mediated arachidonic acid routes affect the outcome of renal transplantation.
Gervasini G et al.
European Journal of Clinical Investigation, 2015
Intakes of omega-3 polyunsaturated fatty acids and blood pressure change over time: Possible interaction with genes involved in 20-HETE and EETs metabolism.
Tagetti A et al.
Prostaglandins & Other Lipid Mediators, 2015
Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan.
Ilyas M et al.
Bmc Genomics, 2015
Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid ω-hydroxylation.
Saito T et al.
Drug Metabolism and Pharmacokinetics, 2015
The effect of a single nucleotide polymorphism of the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acid excretion after weight loss.
Ward NC et al.
Journal of Hypertension, 2014
Genetic variation in CYP4A11 and blood pressure response to mineralocorticoid receptor antagonism or ENaC inhibition: an exploratory pilot study in African Americans.
Laffer CL et al.
Journal of the American Society of Hypertension : Jash, 2014
CYP4A11 gene T8590C polymorphism is associated with essential hypertension in the male western Chinese Han population.
Yang H et al.
Clinical and Experimental Hypertension (new York, N.y. : 1993), 2014
Cytochromes p450: roles in diseases.
Pikuleva IA et al.
The Journal of Biological Chemistry, 2013
CYP4A11 variant is associated with high-density lipoprotein cholesterol in women.
White CC et al.
The Pharmacogenomics Journal, 2013
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.
Carey RM et al.
Hypertension (dallas, Tex. : 1979), 2012
Sequencing and analysis of a South Asian-Indian personal genome.
Gupta R et al.
Bmc Genomics, 2012
Arachidonic acid ω-hydroxylase CYP4A11: inter-ethnic variations in the 8590T>C loss-of-function variant.
Lino Cardenas CL et al.
Molecular Biology Reports, 2012
Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.
Lino Cardenas CL et al.
Gene, 2011
Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population.
Ding H et al.
Pharmacogenetics and Genomics, 2010
CYP4A11 polymorphism correlates with coronary endothelial dysfunction in patients with coronary artery disease--the ENCORE Trials.
Hermann M et al.
Atherosclerosis, 2009
Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure.
Liu X et al.
Kidney International, 2009
A polymorphism regulates CYP4A11 transcriptional activity and is associated with hypertension in a Japanese population.
Sugimoto K et al.
Hypertension (dallas, Tex. : 1979), 2008
Association of a CYP4A11 variant and blood pressure in black men.
Gainer JV et al.
Journal of the American Society of Nephrology : Jasn, 2008
The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure.
Fava C et al.
Hypertension (dallas, Tex. : 1979), 2008
A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure.
Ward NC et al.
Hypertension (dallas, Tex. : 1979), 2008
Genetic polymorphisms and haplotype structures of the CYP4A22 gene in a Japanese population.
Hiratsuka M et al.
Mutation Research, 2006
Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy.
Mayer B et al.
Hypertension (dallas, Tex. : 1979), 2005
Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.
Gainer JV et al.
Circulation, 2005
Highly polymorphic human CYP4A11 gene.
Cho BH et al.
Journal of Human Genetics, 2005