Varaico: Literature-Extracted Genetic Variants

Gene:CYP4F2
Variant:p.L519M
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CYP4F2

NM_001082.5:p.L519M

Associated Papers

PharmVar GeneFocus: CYP4F2.

Zubiaur P et al.

Clinical Pharmacology and Therapeutics, 2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM2_ESM.xlsx › Sheet1

Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8380 Japanese Subjects and Assessment of Arachidonic Acid ω-Hydroxylation.

Sato Y et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM4_ESM.xlsx › Novel_Previously_described_var.

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

P450 Pharmacogenetics in Indigenous North American Populations.

Henderson LM et al.

Journal of Personalized Medicine, 2018

Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance.

Werk AN et al.

Clinical Pharmacology and Therapeutics, 2014

Absence of novel CYP4F2 and VKORC1 coding region DNA variants in patients requiring high warfarin doses.

Burmester JK et al.

Clinical Medicine & Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."