Varaico: Literature-Extracted Genetic Variants

Gene:CYP4F2
Variant:p.W12G
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CYP4F2

NM_001082.5:p.W12G

Associated Papers

Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.

Twesigomwe D et al.

Scientific Reports, 2025

41298791 (PubMed )
Supplement: 41598_2025_26258_MOESM3_ESM.docx

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc6.xlsx › Sheet1

PharmVar GeneFocus: CYP4F2.

Zubiaur P et al.

Clinical Pharmacology and Therapeutics, 2024

Cytochrome P450 Family 4F2 and 4F11 Haplotype Mapping and Association with Hepatic Gene Expression and Vitamin K Hydroxylation Activity.

Alade AN et al.

Acs Pharmacology & Translational Science, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8380 Japanese Subjects and Assessment of Arachidonic Acid ω-Hydroxylation.

Sato Y et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

The pharmacogenomic landscape of an Indigenous Australian population.

Samarasinghe SR et al.

Frontiers in Pharmacology, 2023

37284308 (PubMed )
Supplement: Table3.xlsx › HGMD-ClinVar_14_known_variants

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies' adaptive sampling.

Deserranno K et al.

Frontiers in Pharmacology, 2023

38026945 (PubMed )
Supplement: DataSheet1.ZIP › SupplementaryMaterials › SupplementaryMaterials_Tables_S4-S9.xlsx › HG002_R10.4.1_AldyCalls

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Case report: Two unique nonsense mutations in HTRA1-related cerebral small vessel disease in a Chinese population and literature review.

Chen W et al.

Frontiers in Neurology, 2022

36619910 (PubMed )
Supplement: Data_Sheet_6.ZIP › case2-C › 3.________ › CA2275B________.____Exonic_Variants.xlsx › sheet1

Genetic analysis of pharmacogenomic VIP variants in the Wa population from Yunnan Province of China.

Li D et al.

Bmc Genomic Data, 2021

Combination of Genome-Wide Polymorphisms and Copy Number Variations of Pharmacogenes in Koreans.

Han N et al.

Journal of Personalized Medicine, 2021

Identification of novel CYP4F2 genetic variants exhibiting decreased catalytic activity in the conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).

Kim WY et al.

Prostaglandins, Leukotrienes, and Essential Fatty Acids, 2018

CYP4F2 affects phenotypic outcome in adrenoleukodystrophy by modulating the clearance of very long-chain fatty acids.

van Engen CE et al.

Biochimica Et Biophysica Acta, 2016

Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.

Pratt VM et al.

The Journal of Molecular Diagnostics : Jmd, 2016

Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX.

Fohner AE et al.

Pharmacogenetics and Genomics, 2015

The revised human liver cytochrome P450 "Pie": absolute protein quantification of CYP4F and CYP3A enzymes using targeted quantitative proteomics.

Michaels S et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2014

Genetic polymorphism of cytochrome P450 4F2, vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials.

Athinarayanan S et al.

Plos One, 2014

Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.

Flanagan JM et al.

Blood, 2013

Integrating precision medicine in the study and clinical treatment of a severely mentally ill person.

O'Rawe JA et al.

Peerj, 2013

24109560 (PubMed )
Supplement: peerj-01-177-s012.xlsx › all_drug.csv

Absence of novel CYP4F2 and VKORC1 coding region DNA variants in patients requiring high warfarin doses.

Burmester JK et al.

Clinical Medicine & Research, 2011

Genes involved in the metabolism of poly-unsaturated fatty-acids (PUFA) and risk for Crohn's disease in children & young adults.

Costea I et al.

Plos One, 2010

Common variants of cytochrome P450 4F2 exhibit altered vitamin E-{omega}-hydroxylase specific activity.

Bardowell SA et al.

The Journal of Nutrition, 2010

Association of a functional cytochrome P450 4F2 haplotype with urinary 20-HETE and hypertension.

Liu H et al.

Journal of the American Society of Nephrology : Jasn, 2008

Functional polymorphism in human CYP4F2 decreases 20-HETE production.

Stec DE et al.

Physiological Genomics, 2007

Japanese single nucleotide polymorphism database for 267 possible drug-related genes.

Iida A et al.

Cancer Science, 2006

[SNP collection, pharmacogenomics, and the future of drug therapy].

Iida A et al.

Gan to Kagaku Ryoho. Cancer & Chemotherapy, 2002

906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.

Saito S et al.

Journal of Human Genetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."