Associated Papers
Cytohesin-2 is essential for the perinatal development of mice and regulates Golgi volume.
Küsters C et al.
Life Science Alliance, 2026
The protein kinase Akt acts as a coat adaptor in endocytic recycling.
Hsu JW et al.
Nature Cell Biology, 2020
ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment.
Salem JC et al.
Molecular Biology of the Cell, 2015
Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.
Zhai J et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2015
Nm23-H1 regulates glucose-stimulated insulin secretion in pancreatic β-cells via Arf6-Rac1 signaling axis.
Veluthakal R et al.
Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2013
The capping domain in RalF regulates effector functions.
Alix E et al.
Plos Pathogens, 2012
Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation.
Lowery J et al.
The Journal of Biological Chemistry, 2011
The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1.
Siu KY et al.
Plos One, 2011
An Arf1 GTPase mutant with different responses to GEF inhibitors.
Flisiak S et al.
Biochemical and Biophysical Research Communications, 2008
Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors.
DiNitto JP et al.
Molecular Cell, 2007
ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling.
Li CC et al.
Molecular Biology of the Cell, 2007
The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network.
Bouschet T et al.
Journal of Cell Science, 2007
Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.
Mohammad-Qureshi SS et al.
Molecular and Cellular Biology, 2007
A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin.
Esteban PF et al.
The Journal of Cell Biology, 2006
The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site.
Amor JC et al.
The Journal of Biological Chemistry, 2005
The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin.
Li HS et al.
Bmc Cell Biology, 2003
Calcium-regulated exocytosis of dense-core vesicles requires the activation of ADP-ribosylation factor (ARF)6 by ARF nucleotide binding site opener at the plasma membrane.
Vitale N et al.
The Journal of Cell Biology, 2002
A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta-phosphate to destabilize GDP on ARF1.
Béraud-Dufour S et al.
The Embo Journal, 1998