Varaico: Literature-Extracted Genetic Variants

Gene:DCAF1
Variant:p.K194R
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DCAF1

NM_001387579.1:p.K194R

Associated Papers

VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation.

Shin Y et al.

Research Square, 2023

Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.

Ghate NB et al.

Nature Communications, 2023

VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation.

Ghate NB et al.

Oncogene, 2023

DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor.

Schabla NM et al.

Journal of Molecular Cell Biology, 2019

VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.

Kim K et al.

Molecular Cell, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."