Varaico: Literature-Extracted Genetic Variants

Gene:DCK
Variant:p.S74A
Back to variants list

DCK

NM_000788.3:p.S74A

Associated Papers

PTEN deficiency facilitates gemcitabine efficacy in cancer by modulating the phosphorylation of PP2Ac and DCK.

Jiang TY et al.

Science Translational Medicine, 2023

Sensors and Inhibitors for the Detection of Ataxia Telangiectasia Mutated (ATM) Protein Kinase.

Huang C et al.

Molecular Pharmaceutics, 2021

The Role of Deoxycytidine Kinase (dCK) in Radiation-Induced Cell Death.

Zhong R et al.

International Journal of Molecular Sciences, 2016

A crucial role for ATR in the regulation of deoxycytidine kinase activity.

Beyaert M et al.

Biochemical Pharmacology, 2016

Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance.

Bunimovich YL et al.

Plos One, 2014

Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage.

Yang C et al.

Nucleic Acids Research, 2012

Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues.

McSorley T et al.

Febs Letters, 2008

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."