Varaico: Literature-Extracted Genetic Variants

Gene:DCK
Variant:p.A100V
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DCK

NM_000788.3:p.A100V

Associated Papers

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.

Zhou Y et al.

Science Advances, 2021

34516913 (PubMed )
Supplement: sciadv.abi6856_tables_s1_to_s8.zip › sciadv.abi6856_Table_S4.xlsx › Sheet1

Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase.

Coulibaly ST et al.

Plos One, 2015

Redesigning human 2'-deoxycytidine kinase enantioselectivity for L-nucleoside analogues as reporters in positron emission tomography.

Muthu P et al.

Acs Chemical Biology, 2014

Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance.

Bunimovich YL et al.

Plos One, 2014

Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation.

Rossolillo P et al.

Plos Genetics, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."